Krauthammer was a leading figure in the neo-conservative movement.

He is known for his outspoken support for America taking a proactive political and military stance on the global stage, such as in both the Gulf War and the 2003 U.S. invasion of Iraq, and for coining the term "Reagan Doctrine" to describe President Ronald Reagan's approach to Cold War matters.

• He frequently contributed columns to Time Magazine, The Washington Post, and other prominent publications.